Autism Accurately Diagnosed with Brain SPECT Imaging

Autism Accurately Diagnosed with Brain SPECT Imaging

Brain Blood Flow Shows Pattern Consistent with Autism

PR Newswire

COSTA MESA, Calif., April 28, 2017 /PRNewswire/ — The diagnosis of Autism Spectrum Disorder (ASD) relies on history and behavioral observation, lacking reliable biomarkers. Researchers from Amen Clinics and the University of Southern California performed what is believed to be the largest ever analysis of brain SPECT (single photon emission computed tomography) scans, a nuclear medicine study that evaluates blood flow and activity patterns, on 928 persons with ASD obtained 9 different sites to investigate whether these scans distinguish ASD from healthy controls.  The age range of patients were from 13-67 years.  

Using sophisticated machine learning algorithms, high levels of separation were obtained. The areas the most predicted ASD were found in the cerebellum, anterior cingulate gyrus, amygdala, frontal and temporal lobes.

Lead author Daniel Amen, MD, child psychiatrist and founder of Amen Clinics said, “Currently, the diagnosis of ASD includes a clinical history, mental status examination and structured screening tools, leaving clinicians in the dark as to the underlying physiology. At Amen Clinics, we frequently see increased activity in the anterior cingulate, leading to obsessive behavior, and decreases in the temporal lobes and cerebellum, which are often associated with learning issues.  Having SPECT scans on ASD patients has helped us better target treatment.”

This is the first brain SPECT imaging study demonstrating the use of machine learning methods to predict ASD from a HC. These results add to the growing body of literature validating the use of machine learning approaches with functional neuroimaging data to improve prediction and classification of individuals with psychiatric disorders like autism.  Given the heterogeneity of ASD, this approach has important implications in the clinical setting in both the diagnosis, intervention and monitoring of treatment outcomes.

Amen Clinics 
3150 Bristol St. Ste 400
Costa Mesa, CA 92626
P: (949) 266-3700
F: (949) 266-3750

PR Contact:
Natalie Buchoz
P: (949) 266-8659
F: (949) 266-3750 


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SOURCE Amen Clinics, Inc.

RE/MAX Realtor Shane Ray Advises Buyers and Sellers in a Low-Inventory Market

Colorado Springs, CO (PRWEB) April 28, 2017

April through August are usually the hottest months of the year to buy or sell a home. Although there are more houses on the market in the spring, there are typically more buyers than inventory. “Colorado Springs is a military town with four Air Force bases and an Army post, which means there’s a lot of moving in and out of the city,” said Realtor Shane Ray, founder of the Shane Ray Team and a recent recipient of the distinguished RE/MAX LLC Platinum Club award for 2016.

For buyers and sellers in a competitive low-inventory market, Ray, who has been selling homes in the Colorado Springs area for eleven years, lists the following four tips:

No. 1: Add an escalation clause. When there are multiple offers on the table, it is important for the buyer to consider adding an escalation clause to their contract. In essence, the escalation clause states, “In the event of a competing offer higher than the buyer’s offer, buyer agrees to pay $500 – $1,000 over the highest competing offer’s net, not to exceed a certain maximum purchase price.” “The escalation clause definitely gives the buyer an edge in a competitive market,” added Ray.

No. 2: Add an appraisal clause. Similarly, the buyer ought to consider adding an appraisal clause when submitting an offer on a house. This clause states that if the appraised value is lower than the sales price but at least as high as the list price, the buyer agrees to pay the difference between the appraised value and the sales price in cash. “It will cost the buyer more money out of pocket promising to pay higher than the appraised value of the house, but it will give them a better chance at standing out amongst other offers,” noted Ray.

No. 3: For the seller, timing is key. In a low-inventory market where buyers instantly flock to a new house when it hits the market, it is important for the seller to allow 3-4 days for showings before making a decision on which offer they’d like to select. "This timeframe will give the seller the ability to obtain the best possible offer and have options while staying in-step with the fast-moving market,” said Ray.

No. 4: Start the home search early. “Get pre-approved through a lender and consider location, budget and the type of financing that is best suited for your needs. It could take time to find the perfect house in the right price range on which to place a serious offer,” concluded Ray. “Buyers should spend some time observing what happens when homes that match their criteria hit the market so they can be prepared to act quickly.”

About Shane Ray, RE/MAX Properties, Inc.

Shane Ray has lived in Colorado Springs since 1983 and has been helping people in the Springs area buy and sell homes since 2006. He has achieved Quality Service Certified Platinum status, which is the highest level of service achievement in the real estate industry. For more information, please call (719) 447-7915, or visit His office is located at 1740 Chapel Hills Drive, Colorado Springs, CO 80920.

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Orthopedic Doctor Has the Bees’ Knees


Orthopedic Doctor Has the Bees’ Knees

PR Newswire

DALLAS, April 28, 2017 /PRNewswire/ — Dr. Craig Callewart, renowned spine surgeon, has a secret life: bees. Dr. Callewart is also a beekeeper, and has over 150,000 bees that he deals with daily.

“Beekeeping has been a hobby since high school and it fascinates me how 30,000 to 50,000 bees can live in a 16-cubic-foot space and fly up to 5 miles to find nectar, water, and pollen,” says Dr. Callewart.

As an orthopedic surgeon, his patients deal with pain on a daily basis, and he understands the medicinal properties of honey. The secret life of bees resides on his family’s cattle ranch in Kaufman, Texas, where he also has llamas.

“The organization and efficiency of a bee colony is fascinating,” says Dr. Callewart. “We, as a society, could learn a lot from their lifestyle.”

Dr. Craig Callewart offices in Dallas, Texas, and has been an orthopedic surgeon for over 25 years. His solo practice gives him the personal space to work with patients on a one-on-one basis so that the patient care is primary. His parents were also in medicine, and they moved here after the Korean War; his father an orthopedic surgeon while his mother was a nurse. Dr. Callewart grew up in Dallas and then attended Texas A&M University, trained at Southwestern in Dallas, along with a residency apprenticeship at Case Western Reserve University, and UCLA.

Honey is nectar that is enzymatically converted and dehydrated to form the complex carbohydrate that we call honey. Two million flowers must be visited, 55,000 miles traveled, 10,000 workers engaged to make just 1 pound of honey. During the dehydration phase of production, one can hear the hives buzzing from yards away as thousands of bees are beating their wings inside the hive to move enough air through the combs. My hives will each produce about 30 pounds of honey — representing 1.5 million miles of flying! The numbers become astronomical — like stars in the sky, and that is part of the fascination for me.

Dr. Callewart specializes in the treatment of painful neck and back conditions, “wear and tear” spine problems, and chronic spinal pain. His clinical interests also include the shoulder pain and hip pain, as this can radiate from the neck or the back. Dr. Callewart believes that while there have been tremendous advancements over the years in how surgeons treat patients with spine conditions, the importance of the bond of trust between the patient and physician remains the same.           

For more information about Dr. Callewart: 
Dr. Callewart specializes in the treatment of disc problems in neck and back, traumatic spine injuries, and chronic spinal pain. His clinical interests include the alleviation of chronic pain associated with spine injuries, wear and tear, scoliosis, cervical and lumbar disc herniations, and the advances in treatment of complicated cases, where previous surgery did not help. For more information, please visit his website:

For more information, contact:

Diana Petrik, Universal Media Group

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