Astellas and Universal Cells, Inc. Announce a Collaboration Utilizing Universal Donor Cell Technology

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Astellas and Universal Cells, Inc. Announce a Collaboration Utilizing Universal Donor Cell Technology

PR Newswire

TOKYO, Oct. 19, 2017 /PRNewswire/ — Astellas Pharma Inc. (TSE: 4503, President and CEO: Yoshihiko Hatanaka, “Astellas”) and Universal Cells, Inc. (CEO: Claudia Mitchell, “Universal Cells”) today announced that Astellas Institute for Regenerative Medicine (“AIRM”) and Universal Cells have entered into an exclusive worldwide license agreement to research, develop and commercialize a novel cell therapy for an undisclosed indication. The collaboration will utilize Universal Cells’ Universal Donor Cell technology to create cell therapy products that can be administered to any recipient without the need for Human Leukocyte Antigen (HLA) matching.

Astellas is a pharmaceutical company dedicated to improving the health of people around the world. (PRNewsFoto/Astellas Pharma Inc.)

“I am pleased to enter into this collaboration with Universal Cells for a novel cell therapy using their proprietary Universal Donor Cell technology based on gene editing by rAAV (recombinant Adeno-Associated Virus) and cell engineering of pluripotent stem cells,” said Yoshitsugu Shitaka, Ph.D., president of AIRM. “This is definitely an important step forward in developing a potential new option as an innovative cell therapy to treat devastating diseases with high unmet medical needs.”

While the research will be conducted jointly by AIRM and Universal Cells, Astellas will lead and fully fund the development program and will obtain worldwide rights for commercialization. In consideration for the collaboration and grant of rights, under the terms of the agreement, Universal Cells is eligible to receive up to $9 million in a combination of an upfront payment and research milestones. Universal Cells is also eligible to receive research funding and further clinical development and regulatory milestone payments of up to $115 million, as well as royalties.

“The commitment of Astellas to the field of Regenerative Medicine is a testimony to their vision to turn innovative science into value for patients,” said Claudia Mitchell, CEO of Universal Cells, Inc. “This research collaboration will leverage Universal Cells unique approach to major challenge of cell therapies – the immune rejection of allogeneic cells. We look forward to bringing real world Regenerative Medicine treatments to the market with Astellas.”

About Astellas Institute for Regenerative Medicine (AIRM)
The Astellas Institute for Regenerative Medicine (AIRM) was established in May 2016 following Astellas’ acquisition of Ocata Therapeutics. Headquartered in Marlborough, Mass., and supported by a research team in Tsukuba, Japan, AIRM is a wholly-owned subsidiary of Astellas and serves as the Company’s global hub for regenerative medicine and cell therapy research in ophthalmology and other therapeutic areas that have few or no available treatment options.

Together with AIRM, Astellas is focused on early discovery of cell therapy products for a variety of diseases through a combination of in-house research and external collaborations, using existing technologies and the creation of proprietary technologies.

About Astellas
Astellas Pharma Inc., based in Tokyo, Japan, is a company dedicated to improving the health of people around the world through the provision of innovative and reliable pharmaceutical products. We focus on Urology, Oncology, Immunology, Nephrology and Neuroscience as prioritized therapeutic areas while advancing new therapeutic areas and discovery research leveraging new technologies/modalities. We are also creating new value by combining internal capabilities and external expertise in the medical/healthcare business. Astellas is on the forefront of healthcare change to turn innovative science into value for patients. For more information, please visit our website at www.astellas.com/en.

About Universal Cells, Inc.
Universal Cells, Inc. is a Seattle-based biotech developing, licensing and commercializing stem cell therapies that overcome immune rejection and can be used to create true off-the-shelf therapeutic products. Using the company’s proprietary genome editing approach, the company engineers stem cells to prevent expression of polymorphic human leukocyte antigen (HLA) molecules, removing the cause of donor tissue rejection and creating Universal Donor Stem Cells that are compatible with every patient. For more information: http://www.universalcells.com.

Cautionary Notes
In this press release, statements made with respect to current plans, estimates, strategies and beliefs and other statements that are not historical facts are forward-looking statements about the future performance of Astellas. These statements are based on management’s current assumptions and beliefs in light of the information currently available to it and involve known and unknown risks and uncertainties. A number of factors could cause actual results to differ materially from those discussed in the forward-looking statements. Such factors include, but are not limited to: (i) changes in general economic conditions and in laws and regulations, relating to pharmaceutical markets, (ii) currency exchange rate fluctuations, (iii) delays in new product launches, (iv) the inability of Astellas to market existing and new products effectively, (v) the inability of Astellas to continue to effectively research and develop products accepted by customers in highly competitive markets, and (vi) infringements of Astellas’ intellectual property rights by third parties.

Information about pharmaceutical products (including products currently in development) which is included in this press release is not intended to constitute an advertisement or medical advice.

 

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SOURCE Astellas Pharma Inc.

CyberTech Systems and Software and Esri Agree to Power GeoShield, Intelligence Led Policing Spatial Analytics with ArcGIS Server via OEM

CyberTech Systems and Software and Esri Agree to Power GeoShield, Intelligence Led Policing Spatial Analytics with ArcGIS Server via OEM

PR Newswire

OAK BROOK, Ill., Oct. 19, 2017 /PRNewswire/ – CyberTech Systems and Software, a leader in providing next-generation Spatial and Advanced Analytic Solutions and Digitalization platforms and Esri, pioneering ArcGIS, the world’s most powerful mapping and analytics software have entered into an OEM agreement to fully embed ArcGIS Server into GeoShield, CyberTech’s Advanced Intelligence Led Policing platform.

CyberTech’s Advanced Intelligence Led Policing platform GeoShield, consolidates crime management data with location mapping and spatial analytics in real time equipping law enforcement agencies with actionable intelligence to improve public safety.

Vince Rosales, GeoShield Division VP at CyberTech says, “Our OEM agreement with Esri to embed ArcGIS Server into GeoShield provides an unprecedented cost effective opportunity for agencies of any size to realize the benefits of real time information access, visualization and spatial analysis to drive their Intelligence Led Policing mission!”

“Integrating ArcGIS within GeoShield allows agencies to gain real-time and actionable intelligence from their data using Esri’s powerful spatial analytics,” said Ryan Lanclos, Public Safety Team Lead at Esri. “With this partnership, GeoShield goes beyond simple crime mapping. It provides the tools law enforcement agencies need to make data driven decisions about where to apply resources. We’re excited to continue a long-standing partnership with CyberTech in the public safety community.”

About CyberTech: CyberTech is a leader in Enterprise Spatial Analytics. Our strategic partnerships with the world’s leading technology corporations SAP, Esri, Microsoft and Cisco are aimed at enabling enterprises to integrate location analytics seamlessly into their business environment. Visit us at www.cybertech.com. For GeoShield, www.geoshield.com.

About Esri: Esri, the global market leader in geographic information system (GIS) software, offers the most powerful mapping and spatial analytics technology available. Since 1969, Esri has helped customers unlock the full potential of data to improve operational and business results. Today, Esri software is deployed in more than 350,000 organizations including the world’s largest cities, most national governments, 75 percent of Fortune 500 companies, and more than 7,000 colleges and universities. Esri engineers the most advanced solutions for digital transformation, the Internet of Things (IoT), and location analytics to inform the most authoritative maps in the world. Visit us at esri.com.

Media Contact: Vince Rosales, geoshield@cybertech.com

 

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SOURCE CyberTech Systems and Software

Formula 1 and SiriusXM Sign Multi-Year Broadcasting Agreement

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Formula 1 and SiriusXM Sign Multi-Year Broadcasting Agreement

SiriusXM will air every FIA Formula One World Championship® Race on satellite radios and the SiriusXM app

Coverage begins with this weekend’s 2017 Formula 1 United States Grand Prix in Austin, Texas, to air nationwide

PR Newswire

NEW YORK, Oct. 19, 2017 /PRNewswire/ — SiriusXM and Formula 1 have entered into a multi-year agreement that makes SiriusXM the exclusive North American radio broadcaster of all Formula 1® (F1®) races, starting with this weekend’s United States Grand Prix. 

SIRIUS XM logo. (PRNewsFoto/SIRIUS XM Radio)

SiriusXM’s coverage of the 2017 Formula 1 United States Grand Prix in Austin, TX will air live this Sunday, October 22 (3:00 pm ET/2:00 pm CT), exclusively on Sirius channel 132, XM channel 203 and channel 963 on the SiriusXM app.  The channels will also carry qualifying on Saturday, October 21 (5:00 pm ET/4:00 pm CT).  Listeners will hear the BBC 5 Live radio broadcast for each race.

The four remaining 2017 Formula 1® races will all air on SiriusXM, including the season-finale 2017 Formula 1 Etihad Abu Dhabi Grand Prix on November 26.  Starting with the 2018 Formula 1 season and beyond SiriusXM will air every Grand Prix race on the calendar.

“Formula 1 races are sensational, world-class events, which showcase the most advanced automotive technology in the hands of exceptional drivers competing on very challenging circuits,” said Scott Greenstein, SiriusXM’s President and Chief Content Officer.  “We are very excited to deliver the excitement of these races to SiriusXM listeners across the country.  As Formula 1 makes its way around the globe, we will bring its fans in North America to each international venue and enable them to follow the action live.”

“We are delighted to have Formula 1 back on SiriusXM,” said Sean Bratches, Managing Director, Commercial Operations at Formula 1.  “Their ability to offer live coverage of all races throughout the Championship to their numerous fans and listeners provides tremendous additional exposure for F1 in the North American market.”

The FIA Formula One World Championship is the highest end of open wheeled motor racing.  The season runs from March through November and this year consists of 20 Grand Prix races run on road course tracks, as well as some closed city streets circuits.  The results of each race are combined to determine two titles, one for drivers and one for constructors (teams). 

Mercedes driver Lewis Hamilton of Great Britain is the top points holder this season (306), ahead of Ferrari driver Sebastian Vettel of Germany (247) and Mercedes driver Valtteri Bottas of Finland (234).  Mercedes, the reigning constructor’s champion, holds the 2017 team points lead.

Formula 1® complements an extensive auto racing lineup on SiriusXM that includes every NASCAR race and every Indy Car Series race, and also expands the amount of European sports programming available to SiriusXM listeners, which already features English Premier League and Champions League soccer.

For more information visit www.SiriusXM.com.

About Formula 1®
Formula 1® racing began in 1950 and is the world’s most prestigious motor racing competition, as well as the world’s most popular annual sporting series. In 2016 it was watched by 400 million unique television viewers from over 200 territories. The 2017 FIA Formula One World Championship™ runs from March to November and spans 20 races in 20 countries across five continents. Formula One World Championship Limited is part of Formula 1, and holds the exclusive commercial rights to the FIA Formula One World Championship™.

Formula 1 is a subsidiary of Liberty Media Corporation (NASDAQ: LSXMA, LSXMB, LSXMK, BATRA, BATRK, FWONA, FWONK) attributed to the Formula One Group tracking stock. 

The F1 FORMULA 1 logo, FORMULA 1, F1, FIA FORMULA ONE WORLD CHAMPIONSHIP, GRAND PRIX and related marks are trade marks of Formula One Licensing BV, a Formula 1 company. All rights reserved.

About SiriusXM
Sirius XM Holdings Inc. (NASDAQ: SIRI) is the world’s largest radio company measured by revenue and has more than 32 million subscribers. SiriusXM creates and offers commercial-free music; premier sports talk and live events; comedy; news; exclusive talk and entertainment, and a wide-range of Latin music, sports and talk programming. SiriusXM is available in vehicles from every major car company and on smartphones and other connected devices as well as online at siriusxm.com. SiriusXM radios and accessories are available from retailers nationwide and online at SiriusXM. SiriusXM also provides premium traffic, weather, data and information services for subscribers through SiriusXM Traffic™, SiriusXM Travel Link, NavTraffic®, NavWeather™. SiriusXM delivers weather, data and information services to aircraft and boats through SiriusXM Aviation™ and SiriusXM Marine™. In addition, SiriusXM Music for Business provides commercial-free music to a variety of businesses. SiriusXM holds a minority interest in SiriusXM Canada which has approximately 2.8 million subscribers. SiriusXM is also a leading provider of connected vehicles services, giving customers access to a suite of safety, security, and convenience services including automatic crash notification, stolen vehicle recovery assistance, enhanced roadside assistance and turn-by-turn navigation.

To download SiriusXM logos and artwork, visit http://www.siriusxm.com/LogosAndPhotos.

This communication contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements include, but are not limited to, statements about future financial and operating results, our plans, objectives, expectations and intentions with respect to future operations, products and services; and other statements identified by words such as “will likely result,” “are expected to,” “will continue,” “is anticipated,” “estimated,” “believe,” “intend,” “plan,” “projection,” “outlook” or words of similar meaning. Such forward-looking statements are based upon the current beliefs and expectations of our management and are inherently subject to significant business, economic and competitive uncertainties and contingencies, many of which are difficult to predict and generally beyond our control. Actual results and the timing of events may differ materially from the results anticipated in these forward-looking statements.

The following factors, among others, could cause actual results and the timing of events to differ materially from the anticipated results or other expectations expressed in the forward-looking statements: our substantial competition, which is likely to increase over time; our ability to attract and retain subscribers, which is uncertain; interference to our service from wireless operations; consumer protection laws and their enforcement; unfavorable outcomes of pending or future litigation; the market for music rights, which is changing and subject to uncertainties; our dependence upon the auto industry; general economic conditions; the security of the personal information about our customers; existing or future government laws and regulations could harm our business; failure of our satellites would significantly damage our business; the interruption or failure of our information technology and communications systems; our failure to realize benefits of acquisitions or other strategic initiatives; rapid technological and industry changes; failure of third parties to perform; our failure to comply with FCC requirements; modifications to our business plan; our indebtedness; our principal stockholder has significant influence over our affairs and over actions requiring stockholder approval and its interests may differ from interests of other holders of our common stock; impairment of our business by third-party intellectual property rights; and changes to our dividend policies which could occur at any time. Additional factors that could cause our results to differ materially from those described in the forward-looking statements can be found in our Annual Report on Form 10-K for the year ended December 31, 2016, which is filed with the Securities and Exchange Commission (the “SEC”) and available at the SEC’s Internet site (

http://www.sec.gov

). The information set forth herein speaks only as of the date hereof, and we disclaim any intention or obligation to update any forward looking statements as a result of developments occurring after the date of this communication.

Source: SiriusXM

Media contacts:
Andrew FitzPatrick
SiriusXM
212-901-6693
Andrew.FitzPatrick@SiriusXM.com 

F1 media contact:
Norman Howell, Director of Communications, Formula 1
E: nhowell@fomltd.com 
M: +44 (0)7920 181 929

Formula 1 Press Office
E: f1media@f1.com

Edelman Press Office
E: Formula1@edelman.com

Formula 1 and SiriusXM Sign Multi-Year Broadcasting Agreement

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SOURCE Sirius XM Holdings Inc.